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KMID : 0616119830140040161
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Korean Journal of Pharmacognosy
1983 Volume.14 No. 4 p.161 ~ p.169
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Studies on the Efficacy of Combined Preparation of Crude Drugs ( ⅩⅤ ) Effects of “ Samulanshin - Tang ”on the Central Nervous System and Isolated Ileum
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홍남두/Hong ND
이경섭/황의완/김남재/Lee KS/Whang WW/Kim NJ
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Abstract
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Although the "Samulanshin-Tang" has been widely used in clinical purposes in the oriental medicine, its clinical efficacy is only documented for the case of palpitation in the Oriental medical reference. The present experiments were undertaken to investigate the clinical efficacy of "Samulanshin-Tang" comparing effects with animal experiments and to validate its orintal medicine description. Following results were obtained; 1) Suppressive action was shown on convulsion due to cerebrocortical and diencephalic causes in Fraction I and II, but no such action was noted myelic causes in mice. 2) Sedative, analgesic and antipyretic actions were noted by Fraction III. 3) Relaxing action was shown on the isolated ileum in mice and antagonistic action was seen on acetylcholine and BaCl₂-induced contractions of the ilem that the direct action of the intestinal smooth muscle was recognized in mice and rats.
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